Peptide “drugs” initially played only the role of hormone analogs to balance disorders. This work focusing on the current state-of-the-art short peptide-based therapeutical developments is the first global review written by researchers from all continents, as a celebration of 100 years of peptide therapeutics since the commencement of insulin therapy in the 1920s. They have aroused considerable interest due to their unique features and great promise in innovative bio-therapies. Short peptides include fundamental molecular information for a prelude to the symphony of life. ![]() They act as signaling entities via all domains of life and interfere with protein-protein interactions, which are indispensable in bio-processes. ![]() ![]() Peptides are fragments of proteins that carry out biological functions.
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